Feature :

• High Solubility & Low Viscosity

Greater solubility and lower viscosity than liquid phase HPLC for faster column equilibration, faster separations and higher productivity.

• Wide Molecular Structure Coverage

Applicable to a wide range of molecular structures with a wide range of polarities from strongly hydrophobic to strongly hydrophilic.

• Environment-Friendly

SFC uses ‘green’ separation solvents – generally CO2 with alcoholic modifiers – which are much greener than other solvents generally used in HPLC.

• Cost-Effective

Dramatic reduction in solvent costs for both purchase and disposal.

• Simple Operation

SFC easily scales-up from analytical to preparative, method transfer is simple and robust for both chiral and achiral sample purification.

• Optimized

JASCO has been developing packed column SFC and SFE systems for more than 30 years; this evolution has resulted in a user-friendly, robust and powerful SFC-4000 Series.

• Flexible

All SF-4000 series SFC systems can be used for HPLC – simply switch off the cooling and BPR.

• Fast Response Back Pressure Regulator

The BP-4340 high-speed dynamic back-pressure regulator ensures an accurate and constant back pressure (typically within a few psi), regardless of flow rate and with virtually no hysteresis. The extremely low dead volume prevents fractions from remixing and precipitation build-up in the flow line.

• Wide Range of Detectors

Fluorescence, UV-visible, Photometric Diode Array (PDA) and Chiral optical detectors. Non-optical detectors include FID, ELSD and single-quad mass-spec.

• Integrated Modular System

A basic system for each scale can be adapted to suit any application. From modifier selection to column heater type to detector combinations.

• Compatible

JASCO SFC systems are compatible with most Mass Spectrometers and offer integrated control with both Advion CMS and Sciex Analyst.

• Flexible Configurations

The three individual platforms for analytical, semi-prep and preparative scales can be customized to suit all applications.